Brisk fall days mean a welcome return to soft fleece layers, cozy socks – and a yearning for grilled cheese sandwiches. But our nostalgia-fueled appetites go beyond mom’s basic lunch offering, made with Town Talk bread and paired with Campbell’s tomato soup. These Pittsburgh spots up the wow factor with savory additions and flavor profiles, oozing with cheesy goodness.

1. Bier’s Pub, 900 Western Ave., North Side

The munchy-crunchy Loaded Grilled Cheese at Bier’s Pub features Cheddar cheese and bacon between thick slices of bread. Grilled poblano peppers, onions and tomatoes add another level of flavor, texture and color. Choose from a bunch of sides — such as Broccoli Salad kicked up with wasabi, Pesto Pasta Salad and Bourbon Baked Beans — or follow our lead to the Bacon Fat Home Fries with peppers and onions.

Bier’s Pub is the exclusive spot to sample drafts from brewer Jake Bier’s War Streets Brewery. A few guest taps are offered, too. Sample a flight of four or six, then fill up a growler or howler of your fave to take home.

Pimento Cheese Melt with Smashed Potato Salad at The Abbey on Butler Street. Photo by Sally Quinn.

2. The Abbey on Butler Street, 4635 Butler St., Lawrenceville

You’d be hard-pressed to find a prettier setting to enjoy a grilled cheese sandwich than the patio at The Abbey on Butler Street. A trickling fountain surrounded by flowers, hanging baskets of waving ferns and black wrought iron add to the ambiance that sends our imaginations to a New Orleans courtyard.

The Pimento Cheese Melt adds a Southern flair to its grilled cheese offering, too. This sandwich is built from pimento cheese spread and Pittsburgh dill pickles on house-baked sourdough bread. Keep it vegetarian or opt for adding pulled bacon — savory slow-cooked pork belly — and you’ve got a winner. Sides include a cool Mashed Potato Salad. Or substitute fries, greens or the addictive Hog & Vin Tots, a grownup version of tater tots that are soaked in a tangy hot bacon vinaigrette.

The Build Your Own Grilled Cheese at Provision PGH in Federal Galley. Photo by Sally Quinn.

3. Provision PGH at Federal Galley, 200 Children’s Way, North Side

Federal Galley is all about choices. The site’s five incubator restaurants allow diners to sample an appetizer from one kitchen, an entrée from another and maybe a dessert along the way.

The Build Your Own Grilled Cheese at Provision PGH takes choice a bit further. The sandwich begins with American and Cheddar between slices of sourdough bread. And then the magic begins with all the special touches you could imagine. Go big with a Wagyu Smash Burger or healthy with  sautéed greens. Caramelized onion, roasted tomatoes, bleu cheese and goat cheese are other tasty options for a grilled cheese that’s bursting with flavor. Thin-cut Triple Cooked Fries arrive alongside your sandwich.

Time your visit for happy hour from 4:30 to 6:30 p.m. Tuesdays through Fridays and enjoy half-off craft beer, wine and cocktails like the Deja Blu, Parliament Tropidelic and Eye of the Walrus.

Los Pollos Hermanos. Photo courtesy of The Yard.

4. The Yard: An American Gastropub, multiple locations

The heart of Pittsburgh’s greatest grilled cheese sandwiches can be found at any of The Yard’s locations, where the menu has a complete section dedicated to cheesy heaven. The lineup lists 22 variations with fun names that are as creative as the minds in the kitchen.

The Big Che-Bowski includes applewood smoked bacon and an over-easy egg with Cheddar, smoked gouda and tomato. The Cheesy Capresey goes the Italian route with Roma tomatoes, basil, fresh mozzarella and provolone, then given flavor flair from a balsamic reduction and infused white truffle oil. Hankering for a cheesesteak? It’s Always Sunny in Philadelphia is a grilled cheese version of that iconic item. You can find pierogies inside a grilled cheese, mac and cheese on another and even one packed with fried green tomatoes. House seasoned potato chips and a bowl of tomato soup give the most flamboyant sandwiches a touch of cafeteria nostalgia.

BRGR Short Rib Grilled Cheese and Grilled Cheese Bites. Photo by Sally Quinn.

5. BRGR, multiple locations

Grilled cheese is so popular at BRGR, it’s earned a spot on the appetizer menu, too. To construct Grilled Cheese Bites, the kitchen layers provolone, applewood smoked bacon and tomatoes that are drizzled with truffle aioli and pressed between Texas toast before grilling. Cut into four triangles and threaded onto a wooden skewer, the crisp-edged sandwich is served alongside tomato fondue as a flavor reminder of old-school tomato soup.